Glimepiride

Catalog No.: A10430
Kir6.2/SUR inhibitor
Glimepiride is a potent Kir6.2/SUR inhibitor with IC50 of 3.0 nM, 5.4 nM, and 7.3 nM for SUR1, SUR2A and SUR2B, used in the treatment of type 2 diabetes mellitus.
Grouped product items
Product Name Price Stock Qty
Glimepiride 500mg
$60.00
In stock
Glimepiride 1000mg
$100.00
In stock
Glimepiride 2000mg
$180.00
In stock
Glimepiride 5000mg
$400.00
In stock
Glimepiride 10mM * 1mL in DMSO
$60.00
In stock
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Biological Activity
Discription Glimepiride is a potent Kir6.2/SUR inhibitor with IC50 of 3.0 nM, 5.4 nM, and 7.3 nM for SUR1, SUR2A and SUR2B, used in the treatment of type 2 diabetes mellitus.
Targets
Target Value
Product Information
Catalog Num A10430
Formula C24H34N4O5S
Molecular Weight 490.62
CAS Number 93479-97-1
SMILES CCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C
Synonyms Amary
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 10 mg/mL (20.38 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.38 mL 101.91 mL 203.82 mL
0.5 mM 4.08 mL 20.38 mL 40.76 mL
1 mM 2.04 mL 10.19 mL 20.38 mL
5 mM 0.41 mL 2.04 mL 4.08 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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