GNE-317

Catalog No.: A13992
PI3K inhibitor
GNE-317 is a potent PI3K inhibitor that can cross the Blood?? brain barrier; shows potent suppression of the PI3K pathway in the brain of mice with intact BBB.
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Product Name Price Stock Qty
GNE-317 5mg
$90.00
In stock
GNE-317 10mg
$140.00
In stock
GNE-317 50mg
$420.00
In stock
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Biological Activity
Discription GNE-317 is a potent PI3K inhibitor that can cross the Blood?? brain barrier; shows potent suppression of the PI3K pathway in the brain of mice with intact BBB.
Targets
Target Value
Product Information
Catalog Num A13992
Formula C19H22N6O3S
Molecular Weight 414.48
CAS Number 1394076-92-6
SMILES COC1(COC1)C2=C(C)C3=C(S2)C(N4CCOCC4)=NC(C5=CN=C(N)N=C5)=N3
Synonyms GNE317, GNE 317
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 40 mg/mL (96.5 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.13 mL 120.63 mL 241.27 mL
0.5 mM 4.83 mL 24.13 mL 48.25 mL
1 mM 2.41 mL 12.06 mL 24.13 mL
5 mM 0.48 mL 2.41 mL 4.83 mL
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