Ilorasertib

Catalog No.: A20982
ATP-competitive multitargeted kinase inhibitor
Ilorasertib (ABT-348) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively.
Grouped product items
Product Name Price Stock Qty
Ilorasertib 1mg
$63.00
In stock
Ilorasertib 5mg
$189.00
In stock
Ilorasertib 10mg
$322.00
In stock
Ilorasertib 50mg
$966.00
In stock
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Biological Activity
Discription Ilorasertib (ABT-348) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively.
Targets
Target Value
Product Information
Catalog Num A20982
Formula C25H21FN6O2S
Molecular Weight 488.54
CAS Number 1227939-82-3
SMILES O=C(NC1=CC=CC(F)=C1)NC2=CC=C(C3=CSC4=C3C(N)=NC=C4C5=CN(CCO)N=C5)C=C2
Synonyms ABT-348, ABT348, ABT 348
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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