INCB3344

Catalog No.: A11465
CCR2 antagonist
INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
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Product Name Price Stock Qty
INCB3344 5mg
$171.00
In stock
INCB3344 10mg
$295.00
In stock
INCB3344 50mg
$874.00
In stock
INCB3344 100mg
$1,748.00
In stock
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Biological Activity
Discription INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
Targets
Target Value
Product Information
Catalog Num A11465
Formula C29H34F3N3O6
Molecular Weight 577.59
CAS Number 1262238-11-8
SMILES CCO[C@H]1CN([C@]2([H])CC[C@@](CC2)(C3=CC4=C(OCO4)C=C3)O)C[C@@H]1NC(CNC(C5=CC(C(F)(F)F)=CC=C5)=O)=O
Synonyms INCB 3344, INCB-3344
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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