JAK3 covalent inhibitor-1

Catalog No.: A18926
JAK3 covalent inhibitor
JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.
Grouped product items
Product Name Price Stock Qty
JAK3 covalent inhibitor-1 1mg
$320.00
In stock
JAK3 covalent inhibitor-1 5mg
$960.00
In stock
JAK3 covalent inhibitor-1 10mg
$1,600.00
In stock
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Biological Activity
Discription JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.
Targets
Target Value
Product Information
Catalog Num A18926
Formula C22H17FN6O2S
Molecular Weight 448.47
CAS Number 2300106-50-5
SMILES O=S(N[C@H](C[C@@H]1NC#N)C(C1=C2)=CC=C2C3=C4C(NC=C4)=NC=N3)(C5=CC=CC(F)=C5)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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