KPT-6566
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | KPT-6566, a potent prolyl isomerase PIN1 inhibitor, covalently binds to the catalytic site of PIN1, selectively inhibits and degrades PIN1. KPT-6566 shows an IC50 of 640?nM and a Ki of 625.2 nM for PIN1 PPIase domain. Anti-cancer activity. |
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Catalog Num | A19126 |
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Formula | C22H21NO5S2 |
Molecular Weight | 443.54 |
CAS Number | 881487-77-0 |
SMILES | O=C(O)CSC(C1=O)=C/C(C2=C1C=CC=C2)=N\S(=O)(C3=CC=C(C(C)(C)C)C=C3)=O |
Synonyms | KPT 6566; KPT6566 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2