KRX-0402

Catalog No.: A15459
DNA repair inhibitor
KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin?€?s lymphoma.
Grouped product items
Product Name Price Stock Qty
KRX-0402 5mg
$150.00
In stock
KRX-0402 10mg
$280.00
In stock
KRX-0402 25mg
$550.00
In stock
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Biological Activity
Discription KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin?€?s lymphoma.
Product Information
Catalog Num A15459
Formula C12H11N5O
Molecular Weight 241.25
CAS Number 1000874-21-4
SMILES NC1=NC(OCC2=CC=CC=C2)=C3NC=NC3=N1
Synonyms O6-benzyl guanine, O6-BG
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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