LF3

Catalog No.: A16851
Wnt inhibitor
LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 with an IC50 less than 2 μM.
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LF3 5mg
LF3 10mg
LF3 50mg
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Biological Activity
Discription LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 with an IC50 less than 2 μM.
Product Information
Catalog Num A16851
Formula C20H24N4O2S2
Molecular Weight 416.56
CAS Number 664969-54-4
SMILES S=C(N1CCN(C/C=C/C2=CC=CC=C2)CC1)NC3=CC=C(S(=O)(N)=O)C=C3
Synonyms LF 3, LF-3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 75 mg/mL (180.05 mM)
Water Insoluble
Ethanol Warmed: 5 mg/mL (12 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.01 mL 120.03 mL 240.06 mL
0.5 mM 4.8 mL 24.01 mL 48.01 mL
1 mM 2.4 mL 12 mL 24.01 mL
5 mM 0.48 mL 2.4 mL 4.8 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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