PF-05175157
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively. |
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Catalog Num | A21460 |
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Formula | C23H27N5O2 |
Molecular Weight | 405.49 |
CAS Number | 1301214-47-0 |
SMILES | O=C1CC2(CCN(C(C3=CC=C4C(NC(C)=N4)=C3)=O)CC2)CC5=C1N(C(C)C)N=C5 |
Synonyms | PF05175157, PF 05175157 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 28 mg/mL (69.05 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.66 mL | 123.31 mL | 246.62 mL |
0.5 mM | 4.93 mL | 24.66 mL | 49.32 mL |
1 mM | 2.47 mL | 12.33 mL | 24.66 mL |
5 mM | 0.49 mL | 2.47 mL | 4.93 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2