PF-4191834

Catalog No.: A18777
5-LOX inhibitor
PF-4191834 is a novel, potent and selective non-redox 5-lipoxygenase inhibitor effective in inflammation and pain with an IC50=229 nM. displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes.
Grouped product items
Product Name Price Stock Qty
PF-4191834 1mg
$220.00
In stock
PF-4191834 5mg
$620.00
In stock
PF-4191834 10mg
$1,100.00
In stock
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Biological Activity
Discription PF-4191834 is a novel, potent and selective non-redox 5-lipoxygenase inhibitor effective in inflammation and pain with an IC50=229 nM. displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes.
Targets
Target Value
Product Information
Catalog Num A18777
Formula C22H23N3O2S
Molecular Weight 393.51
CAS Number 1029317-21-2
SMILES O=C(C1(C2=CC=CC(SC3=CC=C(C4=CC=NN4C)C=C3)=C2)CCOCC1)N
Synonyms PF-04191834; PF04191834; PF 04191834; PF-4191834; PF4191834; PF 4191834.
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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