Polaprezinc

Catalog No.: A18251
Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS).
Grouped product items
Product Name Price Stock Qty
Polaprezinc 10mg
$50.00
In stock
Polaprezinc 50mg
$120.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS).
Product Information
Catalog Num A18251
Formula C9H12N4O3Zn
Molecular Weight 289.6
CAS Number 107667-60-7
SMILES O=C1[C@@H](N2C(CC[NH2][Zn]2O1)=O)CC3=CN=CN3
Synonyms Polaprezinc; Z 103.
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Insoluble
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.53 mL 172.65 mL 345.3 mL
0.5 mM 6.91 mL 34.53 mL 69.06 mL
1 mM 3.45 mL 17.27 mL 34.53 mL
5 mM 0.69 mL 3.45 mL 6.91 mL
Useful Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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