SAR125844

Catalog No.: A21094
MET inhibitor
SAR125844 is a potent, highly selective, reversible and ATP-competitive MET receptor tyrosine kinase (RTK) inhibitor, with an IC50 of 4.2 nM. Shows inhibition of MET autophosphorylation in cell-based assays.
Grouped product items
Product Name Price Stock Qty
SAR125844 5mg
$108.00
In stock
SAR125844 10mg
$186.00
In stock
SAR125844 50mg
$552.00
In stock
SAR125844 100mg
$1,104.00
In stock
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Biological Activity
Discription SAR125844 is a potent, highly selective, reversible and ATP-competitive MET receptor tyrosine kinase (RTK) inhibitor, with an IC50 of 4.2 nM. Shows inhibition of MET autophosphorylation in cell-based assays.
Product Information
Catalog Num A21094
Formula C25H23FN8O2S2
Molecular Weight 550.63
CAS Number 1116743-46-4
SMILES O=C(NCCN1CCOCC1)NC2=NC3=CC=C(SC4=NN=C5C=CC(C6=CC=C(F)C=C6)=NN54)C=C3S2
Synonyms SAR 125844, SAR-125844
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 11 mg/mL (19.97 mM)
Water <1 mg/mL
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.16 mL 90.81 mL 181.61 mL
0.5 mM 3.63 mL 18.16 mL 36.32 mL
1 mM 1.82 mL 9.08 mL 18.16 mL
5 mM 0.36 mL 1.82 mL 3.63 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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