SAR245409 (XL765, Voxtalisib)

Catalog No.: A16276
PI3K/mTOR dual inhibitor
SAR245409 is a PI3K/mTOR dual kinase inhibitor XL765 is an orally bioavailable small molecule targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinases in the PI3K/mTOR signaling pathway, with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
SAR245409 5mg
$80.00
In stock
SAR245409 10mg
$140.00
In stock
SAR245409 50mg
$415.00
In stock
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Biological Activity
Discription SAR245409 is a PI3K/mTOR dual kinase inhibitor XL765 is an orally bioavailable small molecule targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinases in the PI3K/mTOR signaling pathway, with potential antineoplastic activity.
Targets
Target Value
Product Information
Catalog Num A16276
Formula C13H14N6O
Molecular Weight 270.29
CAS Number 934493-76-2
SMILES O=C1C(C2=NNC=C2)=CC3=C(C)N=C(N)N=C3N1CC
Synonyms Voxtalisib, XL765, SAR 245409, SAR-245409, XL 765, XL-765
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 53 mg/mL (196.08 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37 mL 184.99 mL 369.97 mL
0.5 mM 7.4 mL 37 mL 73.99 mL
1 mM 3.7 mL 18.5 mL 37 mL
5 mM 0.74 mL 3.7 mL 7.4 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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