SB-742457

Catalog No.: A14092
5-HT6 receptor antagonist
SB-742457 is a selective 5-HT6 receptor antagonist with cognition, memory, and learning-enhancing effects.
Grouped product items
Product Name Price Stock Qty
SB-742457 5mg
$90.00
In stock
SB-742457 10mg
$150.00
In stock
SB-742457 25mg
$300.00
In stock
SB-742457 10mM * 1mL in DMSO
$120.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription SB-742457 is a selective 5-HT6 receptor antagonist with cognition, memory, and learning-enhancing effects.
Targets
Target Value
Product Information
Catalog Num A14092
Formula C19H19N3O2S
Molecular Weight 353.444
CAS Number 607742-69-8
SMILES C1CN(CCN1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC=C4
Synonyms GSK 742457, SB742457, SB 742457, GSK742457, SB-742,457
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 72 mg/mL (203.7 mM)
Water Insoluble
Ethanol 2 mg/mL (5.65 mM)
In vivo 2% DMSO, 48% PEG300, 2% Tween 80 and 48% water 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.29 mL 141.47 mL 282.93 mL
0.5 mM 5.66 mL 28.29 mL 56.59 mL
1 mM 2.83 mL 14.15 mL 28.29 mL
5 mM 0.57 mL 2.83 mL 5.66 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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