Seletalisib (UCB-5857)

Catalog No.: A16797
PI3K inhibitor
Seletalisib is a novel small-molecule inhibitor of PI3Kδ with an IC50 value of 12 nM and shows significant selectivity to PI3Kδ with respect to the other class I PI3K isoforms (between 24- and 303-fold).
Grouped product items
Product Name Price Stock Qty
Seletalisib (UCB-5857) 2mg
$120.00
In stock
Seletalisib (UCB-5857) 5mg
$220.00
In stock
Seletalisib (UCB-5857) 25mg
$600.00
In stock
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Biological Activity
Discription Seletalisib is a novel small-molecule inhibitor of PI3Kδ with an IC50 value of 12 nM and shows significant selectivity to PI3Kδ with respect to the other class I PI3K isoforms (between 24- and 303-fold).
Targets
Target Value
Product Information
Catalog Num A16797
Formula C23H14ClF3N6O
Molecular Weight 482.85
CAS Number 1362850-20-1
SMILES FC(F)(F)[C@@H](C1=CC2=CC=CC(Cl)=C2N=C1C3=CC=C[N+]([O-])=C3)NC4=C5C(C=CC=N5)=NC=N4
Synonyms UCB-5857; UCB 5857; UCB5857; Seletalisib
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 89 mg/mL (184.32 mM)
Water Insoluble
Ethanol 89 mg/mL (184.32 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.71 mL 103.55 mL 207.1 mL
0.5 mM 4.14 mL 20.71 mL 41.42 mL
1 mM 2.07 mL 10.36 mL 20.71 mL
5 mM 0.41 mL 2.07 mL 4.14 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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