VU661013

Catalog No.: A18363
MCL-1 Inhibitor
VU661013 is a MCL-1 Inhibitor Combined with Venetoclax Rescues Venetoclax Resistant Acute Myelogenous Leukemia.
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Product Name Stock
VU661013 5mg
VU661013 10mg
VU661013 50mg
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Biological Activity
Discription VU661013 is a MCL-1 Inhibitor Combined with Venetoclax Rescues Venetoclax Resistant Acute Myelogenous Leukemia.
Targets
Target Value
Product Information
Catalog Num A18363
Formula C39H39Cl2N5O4
Molecular Weight 712.672
CAS Number 2131184-57-9
SMILES C[C@@H]1CN(C(=O)C2=C(C3=C(N12)C(=C(C=C3)Cl)C4=C(N(N=C4C)C)C)CCCOC5=CC(=C(C(=C5)C)Cl)C)C6=CN(C7=C6C=C(C=C7)C(=O)O)C
Synonyms VU661013; VU-661013; VU 661013;
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 93 mg/mL (130.49 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.03 mL 70.16 mL 140.32 mL
0.5 mM 2.81 mL 14.03 mL 28.06 mL
1 mM 1.4 mL 7.02 mL 14.03 mL
5 mM 0.28 mL 1.4 mL 2.81 mL
Useful Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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