Vorasidenib

Catalog No.: A16908
IDH1 Inhibitor
Vorasidenib, also known as AG-881, is a potent and selective orally available inhibitor of mutated forms of both isocitrate dehydrogenase type 1 (IDH1, IDH1 [NADP+] soluble) in the cytoplasm and type 2 (IDH2, isocitrate dehydrogenase [NADP+], mitochondrial) in the mitochondria, with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
Vorasidenib 2mg
$85.00
In stock
Vorasidenib 5mg
$135.00
In stock
Vorasidenib 10mg
$225.00
In stock
Vorasidenib 50mg
$675.00
In stock
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Biological Activity
Discription Vorasidenib, also known as AG-881, is a potent and selective orally available inhibitor of mutated forms of both isocitrate dehydrogenase type 1 (IDH1, IDH1 [NADP+] soluble) in the cytoplasm and type 2 (IDH2, isocitrate dehydrogenase [NADP+], mitochondrial) in the mitochondria, with potential antineoplastic activity.
Product Information
Catalog Num A16908
Formula C14H13ClF6N6
Molecular Weight 414.74
CAS Number 1644545-52-7
SMILES C[C@@H](NC1=NC(C2=NC(Cl)=CC=C2)=NC(N[C@H](C)C(F)(F)F)=N1)C(F)(F)F
Synonyms AG-881, AG 881, AG881
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 75 mg/mL (180.83 mM)
Water Insoluble
Ethanol 75 mg/mL (180.83 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.11 mL 120.56 mL 241.11 mL
0.5 mM 4.82 mL 24.11 mL 48.22 mL
1 mM 2.41 mL 12.06 mL 24.11 mL
5 mM 0.48 mL 2.41 mL 4.82 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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