Signaling Pathway
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| Discription | Withaferin A is a steroidal lactone present in W. somnifera that at 2-25 μM has been shown to bind to and induce aggregation of vimentin intermediate filaments in cultured endothelial cells and fibroblasts, causing apoptosis. | ||
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| Targets |
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| Catalog Num | A16904 |
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| Formula | C28H38O6 |
| Molecular Weight | 470.6 |
| CAS Number | 5119-48-2 |
| SMILES | O=C/1O[C@H](CC(=C\1CO)\C)[C@@H](C)[C@H]6CC[C@@H]4[C@]6(C)CC[C@@H]3[C@]5(C(=O)\C=C/[C@H](O)[C@]52O[C@@H]2C[C@H]34)C |
| Synonyms | WithaferinA, Withaferin-A, NSC 101088, NSC 273757 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 92 mg/mL (195.49 mM) | |
| Water | Insoluble | ||
| Ethanol | 4 mg/mL (8.49 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.25 mL | 106.25 mL | 212.49 mL |
| 0.5 mM | 4.25 mL | 21.25 mL | 42.5 mL |
| 1 mM | 2.12 mL | 10.62 mL | 21.25 mL |
| 5 mM | 0.42 mL | 2.12 mL | 4.25 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
