20(S)-Hydroxycholesterol

Catalog No.: A21850
Smo allosteric activator
20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.
Grouped product items
Product Name Price Stock Qty
20(S)-Hydroxycholesterol 5mg
$80.00
In stock
20(S)-Hydroxycholesterol 10mg
$140.00
In stock
20(S)-Hydroxycholesterol 50mg
$520.00
In stock
20(S)-Hydroxycholesterol 100mg
$880.00
In stock
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Biological Activity
Discription 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.
Targets
Target Value
Product Information
Catalog Num A21850
Formula C27H46O2
Molecular Weight 402.65
CAS Number 516-72-3
SMILES C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1
Synonyms 20α-Hydroxycholesterol
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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