MAK-683

Catalog No.: A16922
EED PPI inhibitor
MAK-683 is a potent inhibitor of embryonic ectoderm development protein (EED) and allosteric inhibitor of polycomb repressive complex 2 (PRC2), with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
MAK-683 5mg
$240.00
In stock
MAK-683 10mg
$420.00
In stock
MAK-683 50mg
$1,200.00
In stock
MAK-683 100mg
$2,100.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription MAK-683 is a potent inhibitor of embryonic ectoderm development protein (EED) and allosteric inhibitor of polycomb repressive complex 2 (PRC2), with potential antineoplastic activity.
Product Information
Catalog Num A16922
Formula C20H17FN6O
Molecular Weight 376.39
CAS Number 1951408-58-4
SMILES CC1=NC=CC=C1C2=CN=C(NCC3=C(F)C=CC4=C3CCO4)N5C2=NN=C5
Synonyms MAK683, MAK 683
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 20 mg/mL (53.13 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.57 mL 132.84 mL 265.68 mL
0.5 mM 5.31 mL 26.57 mL 53.14 mL
1 mM 2.66 mL 13.28 mL 26.57 mL
5 mM 0.53 mL 2.66 mL 5.31 mL
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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