MI-2 (Menin-MLL inhibitor 2)

Catalog No.: A12929
Menin-MLL interaction inhibitor
MI-2 (Menin-MLL inhibitor 2) specifically binds to Menin and inhibits Menin??s interaction with MLL fusion proteins in cells. It can effectively reverse MLL fusion protein?Cmediated leukemic transformation by downregulating the expression of target genes downstream of MLL fusion protein oncogenic activity. MI-2 is a new tool for better understanding MLL-mediated leukemogenesis and represents a new approach for studying the role of Menin as an oncogenic cofactor of MLL fusion proteins.
Grouped product items
Product Name Price Stock Qty
MI-2 (Menin-MLL inhibitor 2) 5mg
$140.00
In stock
MI-2 (Menin-MLL inhibitor 2) 10mg
$200.00
In stock
MI-2 (Menin-MLL inhibitor 2) 25mg
$390.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription MI-2 (Menin-MLL inhibitor 2) specifically binds to Menin and inhibits Menin??s interaction with MLL fusion proteins in cells. It can effectively reverse MLL fusion protein?Cmediated leukemic transformation by downregulating the expression of target genes downstream of MLL fusion protein oncogenic activity. MI-2 is a new tool for better understanding MLL-mediated leukemogenesis and represents a new approach for studying the role of Menin as an oncogenic cofactor of MLL fusion proteins.
Targets
Target Value
Product Information
Catalog Num A12929
Formula C18H25N5S2
Molecular Weight 375.55
CAS Number 1271738-62-5
SMILES CCCC1=CC2=C(N=CN=C2S1)N3CCN(CC3)C4=NCC(S4)(C)C
Synonyms Menin-MLL inhibitor 2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 71 mg/mL (189.05 mM)
Water Insoluble
Ethanol 71 mg/mL (189.05 mM)
In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.63 mL 133.14 mL 266.28 mL
0.5 mM 5.33 mL 26.63 mL 53.26 mL
1 mM 2.66 mL 13.31 mL 26.63 mL
5 mM 0.53 mL 2.66 mL 5.33 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy MI-2 (Menin-MLL inhibitor 2) | MI-2 (Menin-MLL inhibitor 2) Supplier | purchase MI-2 (Menin-MLL inhibitor 2) | MI-2 (Menin-MLL inhibitor 2) cost | MI-2 (Menin-MLL inhibitor 2) manufacturer | order MI-2 (Menin-MLL inhibitor 2) | MI-2 (Menin-MLL inhibitor 2) distributor | buy 1271738-62-5 | 1271738-62-5 Supplier | purchase 1271738-62-5 | 1271738-62-5 cost | 1271738-62-5 manufacturer | order 1271738-62-5 | 1271738-62-5 distributor