MK-0674

Catalog No.: A21558
cathepsin K inhibitor
MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S.
Grouped product items
Product Name Price Stock Qty
MK-0674 1mg
$320.00
In stock
MK-0674 5mg
$960.00
In stock
MK-0674 10mg
$1,600.00
In stock
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Biological Activity
Discription MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S.
Product Information
Catalog Num A21558
Formula C26H27F6N3O2
Molecular Weight 527.5
CAS Number 887781-62-6
SMILES N#CC1(CC1)NC([C@H](CC(C)(C)F)N[C@@H](C2=CC=C(C3=CC=C(C=C3)[C@@H](O)C(F)F)C=C2)C(F)(F)F)=O
Synonyms MK0674, MK 0674
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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