A 740003

Catalog No.: A11316
P2X7 receptor antagonist
A 740003 is a novel competitive antagonist of P2X7 receptors (IC50 values = 40 nM for human and 18 nM for rat).
Grouped product items
Product Name Price Stock Qty
A 740003 10mg
$30.00
In stock
A 740003 25mg
$60.00
In stock
A 740003 50mg
$80.00
In stock
A 740003 100mg
$125.00
In stock
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Biological Activity
Discription A 740003 is a novel competitive antagonist of P2X7 receptors (IC50 values = 40 nM for human and 18 nM for rat).
Product Information
Catalog Num A11316
Formula C26H30N6O3
Molecular Weight 474.6
CAS Number 861393-28-4
SMILES CC(C)(C)C(NC(=O)CC1=CC(=C(C=C1)OC)OC)/N=C(/NC#N)\NC2=CC=CC3=C2C=CC=N3
Synonyms A740003, A-740003
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 85 mg/mL (179.11 mM)
Water Insoluble
Ethanol 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.07 mL 105.35 mL 210.7 mL
0.5 mM 4.21 mL 21.07 mL 42.14 mL
1 mM 2.11 mL 10.54 mL 21.07 mL
5 mM 0.42 mL 2.11 mL 4.21 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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