AZD1390
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | AZD1390 is a first-in-class orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases. | ||
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Catalog Num | A16798 |
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Formula | C27H32FN5O2 |
Molecular Weight | 477.57 |
CAS Number | 2089288-03-7 |
SMILES | O=C(N1C(C)C)N(C)C2=C1C3=CC(C4=CC=C(OCCCN5CCCCC5)N=C4)=C(F)C=C3N=C2 |
Synonyms | AZD-1390, AZD 1390 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 14 mg/mL (29.31 mM) | |
Water | Insoluble | ||
Ethanol | 93 mg/mL (194.73 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.94 mL | 104.7 mL | 209.39 mL |
0.5 mM | 4.19 mL | 20.94 mL | 41.88 mL |
1 mM | 2.09 mL | 10.47 mL | 20.94 mL |
5 mM | 0.42 mL | 2.09 mL | 4.19 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2