ARN-3236

Catalog No.: A18725
SIK2 inhibitor
ARN-3236 is potent, orally active and selective SIK2 inhibitor. ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L.
Grouped product items
Product Name Price Stock Qty
ARN-3236 2mg
$90.00
In stock
ARN-3236 5mg
$130.00
In stock
ARN-3236 10mg
$220.00
In stock
ARN-3236 50mg
$780.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription ARN-3236 is potent, orally active and selective SIK2 inhibitor. ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L.
Targets
Target Value
Product Information
Catalog Num A18725
Formula C19H16N2O2S
Molecular Weight 336.4
CAS Number 1613710-01-2
SMILES COC1=CC=C(C2=CNC3=NC=CC(C4=CSC=C4)=C32)C(OC)=C1
Synonyms ARN-3236; ARN 3236; ARN3236.
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 62 mg/mL (184.3 mM)
Water Insoluble
Ethanol 2 mg/mL (5.94 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.73 mL 148.63 mL 297.27 mL
0.5 mM 5.95 mL 29.73 mL 59.45 mL
1 mM 2.97 mL 14.86 mL 29.73 mL
5 mM 0.59 mL 2.97 mL 5.95 mL
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