Belizatinib

Catalog No.: A20919
ALK/TRKA/TRKB/TRKC inhibitor
Belizatinib is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7?nM for wild-type recombinant ALK kinase.
Grouped product items
Product Name Price Stock Qty
Belizatinib 2mg
$54.00
In stock
Belizatinib 5mg
$108.00
In stock
Belizatinib 10mg
$210.00
In stock
Belizatinib 50mg
$618.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Belizatinib is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7?nM for wild-type recombinant ALK kinase.
Product Information
Catalog Num A20919
Formula C33H44FN5O3
Molecular Weight 577.73
CAS Number 1357920-84-3
SMILES O=C(NC1=NC2=CC=C(CN3CCC(C(C)(O)C)CC3)C=C2N1[C@H]4CC[C@@H](C(NC(C)C)=O)CC4)C5=CC=C(F)C=C5
Synonyms TSR 011, TSR011
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 96 mg/mL (166.17 mM)
Water Insoluble
Ethanol 96 mg/mL (166.17 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.31 mL 86.55 mL 173.09 mL
0.5 mM 3.46 mL 17.31 mL 34.62 mL
1 mM 1.73 mL 8.65 mL 17.31 mL
5 mM 0.35 mL 1.73 mL 3.46 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2

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