BI-4464

Catalog No.: A18894
PTK2/FAK inhibitor
BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC.
Grouped product items
Product Name Price Stock Qty
BI-4464 1mg
$150.00
In stock
BI-4464 5mg
$420.00
In stock
BI-4464 10mg
$700.00
In stock
BI-4464 50mg
$2,100.00
In stock
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Biological Activity
Discription BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC.
Product Information
Catalog Num A18894
Formula C28H28F3N5O4
Molecular Weight 555.55
CAS Number 1227948-02-8
SMILES O=C(NC1CCN(C)CC1)C2=CC=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CC5)=C4C5=O)=N3)C(OC)=C2
Synonyms BI 4464, BI4464
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 23 mg/mL (41.4 mM)
Water Insoluble
Ethanol 12 mg/mL (21.6 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18 mL 90 mL 180 mL
0.5 mM 3.6 mL 18 mL 36 mL
1 mM 1.8 mL 9 mL 18 mL
5 mM 0.36 mL 1.8 mL 3.6 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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