Cediranib maleate

Catalog No.: A21857
VEGFR inhibitor
Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.
Grouped product items
Product Name Price Stock Qty
Cediranib maleate 5mg
$50.00
In stock
Cediranib maleate 10mg
$80.00
In stock
Cediranib maleate 50mg
$300.00
In stock
Cediranib maleate 100mg
$480.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.
Targets
Target Value
Product Information
Catalog Num A21857
Formula C29H31FN4O7
Molecular Weight 566.58
CAS Number 857036-77-2
SMILES O=C(O)/C=C\C(O)=O.FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5
Synonyms AZD-2171 maleate, AZD2171, AZD 2171
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 92 mg/mL (162.37 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.65 mL 88.25 mL 176.5 mL
0.5 mM 3.53 mL 17.65 mL 35.3 mL
1 mM 1.76 mL 8.82 mL 17.65 mL
5 mM 0.35 mL 1.76 mL 3.53 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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