E7449

Catalog No.: A21553
PARP1/PARP2 inhibitor
E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ?50 and ?50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
Grouped product items
Product Name Price Stock Qty
E7449 5mg
$130.00
In stock
E7449 10mg
$223.00
In stock
E7449 50mg
$662.00
In stock
E7449 100mg
$1,325.00
In stock
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Biological Activity
Discription E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ?50 and ?50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
Product Information
Catalog Num A21553
Formula C18H15N5O
Molecular Weight 317.34
CAS Number 1140964-99-3
SMILES O=C1NNC2=C3C1=CC=CC3=NC(CN4CC5=C(C=CC=C5)C4)=N2
Synonyms E-7449, E 7449
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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