Genz-123346 free base

Catalog No.: A15442
GL1 synthase Inhibitor
Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; IC50 for GM1 inhibition is 14 nM.
Grouped product items
Product Name Price Stock Qty
Genz-123346 free base 5mg
$90.00
In stock
Genz-123346 free base 10mg
$150.00
In stock
Genz-123346 free base 25mg
$320.00
In stock
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Biological Activity
Discription Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; IC50 for GM1 inhibition is 14 nM.
Product Information
Catalog Num A15442
Formula C24H38N2O4
Molecular Weight 418.57
CAS Number 491833-30-8
SMILES CCCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O
Synonyms Genz123346
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 77 mg/mL (183.96 mM)
Water Insoluble
Ethanol 77 mg/mL (183.96 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.89 mL 119.45 mL 238.91 mL
0.5 mM 4.78 mL 23.89 mL 47.78 mL
1 mM 2.39 mL 11.95 mL 23.89 mL
5 mM 0.48 mL 2.39 mL 4.78 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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