GNF-6231

Catalog No.: A16849
Porcupine inhibitor
GNF-6231 is a potent, orally active and selective Porcupine inhibitor with IC50 of 0.8 nM.
Grouped product items
Product Name Price Stock Qty
GNF-6231 2mg
$120.00
In stock
GNF-6231 5mg
$170.00
In stock
GNF-6231 10mg
$260.00
In stock
GNF-6231 50mg
$880.00
In stock
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Biological Activity
Discription GNF-6231 is a potent, orally active and selective Porcupine inhibitor with IC50 of 0.8 nM.
Product Information
Catalog Num A16849
Formula C24H25FN6O2
Molecular Weight 448.49
CAS Number 1243245-18-2
SMILES O=C(NC1=NC=C(N2CCN(C(C)=O)CC2)C=C1)CC3=CN=C(C4=CC(F)=NC=C4)C(C)=C3
Synonyms GNF6231, GNF 6231
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 87 mg/mL (193.98 mM)
Water Insoluble
Ethanol 5 mg/mL (11.14 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.49 mL 222.97 mL
0.5 mM 4.46 mL 22.3 mL 44.59 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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