GS967

Catalog No.: A14361
late INa Inhibitor
GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late INa); inhibits ATX-II-induced late I(Na) in ventricular myocytes and isolated hearts with IC(50) values of 0.13 and 0.21 uM, respectively.
Grouped product items
Product Name Price Stock Qty
GS967 5mg
$50.00
In stock
GS967 10mg
$85.00
In stock
GS967 25mg
$150.00
In stock
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Biological Activity
Discription GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late INa); inhibits ATX-II-induced late I(Na) in ventricular myocytes and isolated hearts with IC(50) values of 0.13 and 0.21 uM, respectively.
Product Information
Catalog Num A14361
Formula C14H7F6N3O
Molecular Weight 347.22
CAS Number 1262618-39-2
SMILES FC(F)(F)C1=NN=C2C=CC(C3=CC=C(OC(F)(F)F)C=C3)=CN21
Synonyms GS-967, GS 967
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 38 mg/mL (109.44 mM)
Water Insoluble
Ethanol 39 mg/mL (112.32 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.8 mL 144 mL 288 mL
0.5 mM 5.76 mL 28.8 mL 57.6 mL
1 mM 2.88 mL 14.4 mL 28.8 mL
5 mM 0.58 mL 2.88 mL 5.76 mL
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This equation is commonly abbreviated as: C1V1 = C2V2

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