GSK3368715 (EPZ019997) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)).
Product Information
Catalog Num
A19136
Formula
C20H38N4O2
Molecular Weight
366.54
CAS Number
1629013-22-4
SMILES
CNCCN(CC1=CNN=C1C2CCC(COCC)(COCC)CC2)C
Synonyms
GSK 3368715, GSK-3368715
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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