H3B-6527

Catalog No.: A16252
FGFR4 inhibitor
H3B-6527 is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice.
Grouped product items
Product Name Price Stock Qty
H3B-6527 1mg
$120.00
In stock
H3B-6527 5mg
$320.00
In stock
H3B-6527 10mg
$460.00
In stock
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Biological Activity
Discription H3B-6527 is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice.
Product Information
Catalog Num A16252
Formula C29H34Cl2N8O4
Molecular Weight 629.54
CAS Number 1702259-66-2
SMILES C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O
Synonyms H3B6527, H3B 6527
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 45 mg/mL (71.48 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.88 mL 79.42 mL 158.85 mL
0.5 mM 3.18 mL 15.88 mL 31.77 mL
1 mM 1.59 mL 7.94 mL 15.88 mL
5 mM 0.32 mL 1.59 mL 3.18 mL
Useful Calculator

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