Importazole

Catalog No.: A17128
nuclear transport receptor importin-β inhibitor
Importazole is a cell-permeable inhibitor of importin-β. It specifically inhibits the function of importin-β, likely by altering its interaction with RanGTP.
Grouped product items
Product Name Price Stock Qty
Importazole 5mg
$40.00
In stock
Importazole 10mg
$70.00
In stock
Importazole 50mg
$280.00
In stock
Importazole 100mg
$480.00
In stock
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Biological Activity
Discription Importazole is a cell-permeable inhibitor of importin-β. It specifically inhibits the function of importin-β, likely by altering its interaction with RanGTP.
Product Information
Catalog Num A17128
Formula C20H22N4
Molecular Weight 318.4
CAS Number 662163-81-7
SMILES [H]N(C(C1=CC=CC=C1)C)C2=NC(N3CCCC3)=NC4=C2C=CC=C4
Synonyms IPZ
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 58 mg/mL (182.15 mM)
Water Insoluble
Ethanol 29 mg/mL (91.07 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.41 mL 157.04 mL 314.07 mL
0.5 mM 6.28 mL 31.41 mL 62.81 mL
1 mM 3.14 mL 15.7 mL 31.41 mL
5 mM 0.63 mL 3.14 mL 6.28 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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