IRAK inhibitor 6 (IRAK-IN-6)

Catalog No.: A11460
IRAK inhibitor
IRAK-IN-6, also known as IRAK inhibitor 6, is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. IRAK-4 is reported to be essential for the activation of the intracellular signalling cascades including NF-kB and MAPK pathways, which are critical for the production of inflammatory cytokines.
Grouped product items
Product Name Price Stock Qty
IRAK inhibitor 6 (IRAK-IN-6) 5mg
$260.00
In stock
IRAK inhibitor 6 (IRAK-IN-6) 10mg
$360.00
In stock
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Biological Activity
Discription IRAK-IN-6, also known as IRAK inhibitor 6, is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. IRAK-4 is reported to be essential for the activation of the intracellular signalling cascades including NF-kB and MAPK pathways, which are critical for the production of inflammatory cytokines.
Product Information
Catalog Num A11460
Formula C20H20N4O3S
Molecular Weight 396.46
CAS Number 1042672-97-8
SMILES O=C(C1=CSC(C2=CC=CN=C2)=N1)NC3=CC=C(N4CCOCC4)C=C3OC
Synonyms IRAK-IN-6, IRAK IN 6, IRAKIN6, IRAK inhibitor 6
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 6 mg/mL (15.13 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.22 mL 126.12 mL 252.23 mL
0.5 mM 5.04 mL 25.22 mL 50.45 mL
1 mM 2.52 mL 12.61 mL 25.22 mL
5 mM 0.5 mL 2.52 mL 5.04 mL
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