JNJ-64619178
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | JNJ-64619178 is a PRMT5 inhibitor with high selectivity and potency (subnanomolar range, PRMT5-MEP-50 IC50=0.14 nM) under different in vitro and cellular conditions, paired with favorable pharmacokinetics and safety properties. |
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Catalog Num | A16861 |
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Formula | C22H23BrN6O2 |
Molecular Weight | 483.37 |
CAS Number | 2086772-26-9 |
SMILES | BrC1=C(N)N=C(C=C(CC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(N=CN=C4N)=C4C=C3)C2)C=C5)C5=C1 |
Synonyms | JNJ64619178, JNJ 64619178 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 94 mg/mL (194.47 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.69 mL | 103.44 mL | 206.88 mL |
0.5 mM | 4.14 mL | 20.69 mL | 41.38 mL |
1 mM | 2.07 mL | 10.34 mL | 20.69 mL |
5 mM | 0.41 mL | 2.07 mL | 4.14 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2