PX-478 HCl
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potential antineoplastic activity. PX-478 has excellent activity against established human tumor xenografts, providing tumor regressions with prolonged growth delays which correlate positively with HIF-1 levels. PX-478 is a highly water soluble molecule, with good i.v., i.p. and p.o. antitumor activity. | ||
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Catalog Num | A14319 |
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Formula | C13H20Cl4N2O3 |
Molecular Weight | 394.12 |
CAS Number | 685898-44-6 |
SMILES | C1=CC(=CC=C1C[C@@H](C(=O)O)N)[N+](CCCl)(CCCl)[O-].Cl.Cl |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 73 mg/mL (185.21 mM) | |
Water | 73 mg/mL (185.21 mM) | ||
Ethanol | 73 mg/mL (185.21 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.37 mL | 126.86 mL | 253.73 mL |
0.5 mM | 5.07 mL | 25.37 mL | 50.75 mL |
1 mM | 2.54 mL | 12.69 mL | 25.37 mL |
5 mM | 0.51 mL | 2.54 mL | 5.07 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2