PZ-2891
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively. |
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Catalog Num | A18880 |
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Formula | C20H23N5O |
Molecular Weight | 349.43 |
CAS Number | 2170608-82-7 |
SMILES | N#CC1=NN=C(N2CCN(C(CC3=CC=C(C(C)C)C=C3)=O)CC2)C=C1 |
Synonyms | PZ2891, PZ-2891 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 67 mg/mL (191.73 mM) | |
Water | Insoluble | ||
Ethanol | 1 mg/mL (2.86 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 28.62 mL | 143.09 mL | 286.18 mL |
0.5 mM | 5.72 mL | 28.62 mL | 57.24 mL |
1 mM | 2.86 mL | 14.31 mL | 28.62 mL |
5 mM | 0.57 mL | 2.86 mL | 5.72 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2