PLX51107
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | PLX51107 is a potent and selective BET inhibitor, with Kds of 1.6, 2.1, 1.7, and 5 nM for BD1 and 5.9, 6.2, 6.1, and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively; PLX51107 also interacts with the bromodomains of CBP and EP300 (Kd, in the 100 nM range). |
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Catalog Num | A18345 |
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Formula | C26H22N4O3 |
Molecular Weight | 438.487 |
CAS Number | 1627929-55-8 |
SMILES | C[C@@H](C1=NC=CC=C1)N2C=C(C3=CC=C(C(O)=O)C=C3)C4=NC=C(C5=C(C)ON=C5C)C=C42 |
Synonyms | PLX-51107, PLX 51107 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 84 mg/mL (191.57 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.81 mL | 114.03 mL | 228.06 mL |
0.5 mM | 4.56 mL | 22.81 mL | 45.61 mL |
1 mM | 2.28 mL | 11.4 mL | 22.81 mL |
5 mM | 0.46 mL | 2.28 mL | 4.56 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2