RO8994

Catalog No.: A20865
MDM2 inhibitor
RO8994 is a highly potent and selective series of spiroindolinone small-molecule MDM2 inhibitor, with IC50 of 5 nM (HTRF binding assays) and 20 nM (MTT proliferation assays).
Grouped product items
Product Name Price Stock Qty
RO8994 5mg
$81.00
In stock
RO8994 10mg
$140.00
In stock
RO8994 50mg
$414.00
In stock
RO8994 100mg
$828.00
In stock
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Biological Activity
Discription RO8994 is a highly potent and selective series of spiroindolinone small-molecule MDM2 inhibitor, with IC50 of 5 nM (HTRF binding assays) and 20 nM (MTT proliferation assays).
Product Information
Catalog Num A20865
Formula C31H31Cl2FN4O4
Molecular Weight 613.51
CAS Number 1309684-94-3
SMILES O=C([C@H](N[C@H]1CC(C)(C)C)[C@H](C2=CC=CC(Cl)=C2F)[C@@]31C(NC4=C3C=CC(Cl)=C4)=O)NC5=CC=C(C(N)=O)C=C5OC
Synonyms RO 8994, RO-8994
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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