Rodatristat

Catalog No.: A18820
TPH1/TPH2 inhibitor
Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice.
Grouped product items
Product Name Price Stock Qty
Rodatristat 1mg
$320.00
In stock
Rodatristat 5mg
$960.00
In stock
Rodatristat 10mg
$1,600.00
In stock
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Biological Activity
Discription Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice.
Product Information
Catalog Num A18820
Formula C27H27ClF3N5O3
Molecular Weight 561.98
CAS Number 1673568-73-4
SMILES O=C([C@H]1NCC2(CCN(C3=NC(N)=NC(O[C@H](C4=CC=C(Cl)C=C4C5=CC=CC=C5)C(F)(F)F)=C3)CC2)C1)O
Synonyms KAR5417, KAR-5417, KAR 5417
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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