SB-277011 dihydrochloride

Catalog No.: A21353
dopamine D3 receptor antagonist
SB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively.
Grouped product items
Product Name Price Stock Qty
SB-277011 dihydrochloride 1mg
$320.00
In stock
SB-277011 dihydrochloride 5mg
$960.00
In stock
SB-277011 dihydrochloride 10mg
$1,600.00
In stock
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Bulk Discount
Free Delivery on orders over $500

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Biological Activity
Discription SB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively.
Targets
Target Value
Product Information
Catalog Num A21353
Formula C28H32Cl2N4O
Molecular Weight 511.49
CAS Number 1226917-67-4
SMILES O=C(C1=CC=NC2=CC=CC=C12)N[C@H]3CC[C@H](CCN4CC5=C(C=C(C#N)C=C5)CC4)CC3.[H]Cl.[H]Cl
Synonyms SB-277011A dihydrochloride, SB277011, SB 277011, SB 277011A, SB277011A
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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