SKL2001

Catalog No.: A16707
Wnt/β-catenin agonist
SKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction.
Grouped product items
Product Name Price Stock Qty
SKL2001 10mg
$63.00
In stock
SKL2001 25mg
$126.00
In stock
SKL2001 50mg
$217.00
In stock
SKL2001 100mg
$371.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription SKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction.
Product Information
Catalog Num A16707
Formula C14H14N4O3
Molecular Weight 286.29
CAS Number 909089-13-0
SMILES O=C(C1=NOC(C2=CC=CO2)=C1)NCCCN3C=CN=C3
Synonyms SKL 2001, SKL-2001
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 50 mg/mL (174.64 mM)
Water Insoluble
Ethanol 50 mg/mL (174.64 mM)
In vivo 2% DMSO+40% PEG 300+2% Tween 80+ddH2O 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.93 mL 174.65 mL 349.3 mL
0.5 mM 6.99 mL 34.93 mL 69.86 mL
1 mM 3.49 mL 17.46 mL 34.93 mL
5 mM 0.7 mL 3.49 mL 6.99 mL
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