TRi-1
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | TRi-1 is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy. |
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Catalog Num | A18556 |
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Formula | C12H9ClN2O5S |
Molecular Weight | 328.73 |
CAS Number | 246020-68-8 |
SMILES | O=[N+](C1=CC=C(OC)N=C1S(=O)(C2=CC=C(Cl)C=C2)=O)[O-] |
Synonyms | TRi1 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 25 mg/mL (76.04 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 30.42 mL | 152.1 mL | 304.2 mL |
0.5 mM | 6.08 mL | 30.42 mL | 60.84 mL |
1 mM | 3.04 mL | 15.21 mL | 30.42 mL |
5 mM | 0.61 mL | 3.04 mL | 6.08 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2