VX-661

Catalog No.: A12519
CFTR corrector
VX-661 is another cystic fibrosis transmembrane conductance regulator (CFTR) corrector in development for the treatment of cystic fibrosis.
Grouped product items
Product Name Price Stock Qty
VX-661 5mg
$90.00
In stock
VX-661 10mg
$140.00
In stock
VX-661 25mg
$250.00
In stock
VX-661 50mg
$400.00
In stock
VX-661 10mM * 1mL in DMSO
$153.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's VX-661 has been cited by 2 publications
  • Daichi Hinata, .et al. , Int J Mol Sci, 2023, Jan 24;24(3):2305 PMID: 36768629
  • Kusumika Saha, .et al. , Cell Mol Life Sci, 2022, Sep 27;79(10):530 PMID: 36167862
  • Biological Activity
    Discription VX-661 is another cystic fibrosis transmembrane conductance regulator (CFTR) corrector in development for the treatment of cystic fibrosis.
    Targets
    Target Value
    Product Information
    Catalog Num A12519
    Formula C26H27F3N2O6
    Molecular Weight 520.5
    CAS Number 1152311-62-0
    SMILES CC(C)(CO)C1=CC2=CC(=C(C=C2N1C[C@H](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F
    Synonyms VX661, VX 661
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 95 mg/mL (182.51 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.21 mL 96.06 mL 192.12 mL
    0.5 mM 3.84 mL 19.21 mL 38.42 mL
    1 mM 1.92 mL 9.61 mL 19.21 mL
    5 mM 0.38 mL 1.92 mL 3.84 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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