XL-147 (Pilaralisib)

Catalog No.: A15283
PI3K Inhibitor
XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases.
Grouped product items
Product Name Price Stock Qty
XL-147 5mg
$60.00
In stock
XL-147 10mg
$100.00
In stock
XL-147 25mg
$200.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases.
Targets
Target Value
Product Information
Catalog Num A15283
Formula C25H25ClN6O4S
Molecular Weight 541.02
CAS Number 934526-89-3
SMILES CC(C)(C(=O)NC1=CC(=CC=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=C(C=CC(=C4)OC)Cl)N
Synonyms SAR245408, XL 147, XL147, SAR-245408, SAR 245408, pilaralisib
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 92 mg/mL (170.04 mM)
Water Insoluble
Ethanol Insoluble
In vivo 10 mM HCl in sterile water 0.4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.48 mL 92.42 mL 184.84 mL
0.5 mM 3.7 mL 18.48 mL 36.97 mL
1 mM 1.85 mL 9.24 mL 18.48 mL
5 mM 0.37 mL 1.85 mL 3.7 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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