Signaling Pathway
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| Discription | YF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease. | ||
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| Targets |
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| Catalog Num | A21018 |
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| Formula | C20H22ClF3N2O3 |
| Molecular Weight | 430.85 |
| CAS Number | 1311423-89-8 |
| SMILES | O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(OCC)C=CC=C2OCCN(C)C |
| Synonyms | YF2, YF 2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 78 mg/mL (181.03 mM) | |
| Water | 78 mg/mL (181.03 mM) | ||
| Ethanol | 78 mg/mL (181.03 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.21 mL | 116.05 mL | 232.1 mL |
| 0.5 mM | 4.64 mL | 23.21 mL | 46.42 mL |
| 1 mM | 2.32 mL | 11.6 mL | 23.21 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.64 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
