Signaling Pathway
1A-116 is a specific Rac1 inhibitor, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo.
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| Discription | 1A-116 is a specific Rac1 inhibitor, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo. |
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| Catalog Num | A16965 |
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| Formula | C16H16F3N3 |
| Molecular Weight | 307.32 |
| CAS Number | 1430208-73-3 |
| SMILES | N=C(NC1=CC=CC=C1C(F)(F)F)NC2=CC(C)=CC(C)=C2 |
| Synonyms | 1A116, 1A 116 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
