Methotrexate (Abitrexate)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Methotrexate is a cytotoxic agent that inhibits thymidylate synthetase and de novo purine synthesis. | ||
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Targets |
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Catalog Num | A10021 |
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Formula | C20H22N8O5 |
Molecular Weight | 454.44 |
CAS Number | CAS: 59-05-2 |
SMILES | CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O |
Synonyms | MTX, amethopterin, Rheumatrex, Trexall |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 89 mg/mL (195.84 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.01 mL | 110.03 mL | 220.05 mL |
0.5 mM | 4.4 mL | 22.01 mL | 44.01 mL |
1 mM | 2.2 mL | 11 mL | 22.01 mL |
5 mM | 0.44 mL | 2.2 mL | 4.4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2